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Happy New Year!. 4 responses to “News & Views – 2018 Edition” news. January 3, 2019. Dec 10, 2017. A LOOK AT CITIZENSCONFERENCE FROM A SLATE OF THREE LAYOUTS. Major League Baseball has begun its winter meetings in Las Vegas. The Detroit Tigers are here, looking to add to a talented team.VEGF signaling regulates prometastatic functions of adipocytes.
Vascular endothelial growth factor (VEGF) contributes to tumor progression by promoting angiogenesis and tumor invasion. More recently, VEGF has been proposed to play a role in tumor dormancy and cancer cell re-initiation. However, how VEGF influences tumor cell intravasation and metastasis remains largely unexplored. Here we show that VEGF promotes the prometastatic role of breast adipocytes via VEGF-specific receptor-2 (VEGFR2) in a tumor microenvironment. Intriguingly, all functions are mediated by the phosphatidylinositol-3-kinase (PI3K)-Akt pathway

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